Plasma Microbial Cell-Free DNA Sequencing in Immunocompromised Patients with Pneumonia: A Prospective Observational Study
Clinical Infectious Diseases (October 2023)
Clinical Data
Clinical Study
Therapeutic Advances in Infectious Disease
Clinical utility of plasma microbial cell-free DNA sequencing in determining microbiologic etiology of infectious syndromes in solid organ transplant recipients
Some of the publications and abstracts listed on this page may reference the Karius Spectrum test under it's former name Karius Test. This product was rebranded to Karius Spectrum as of March 17, 2025.
Key Publications
Metagenomic Next-Generation Sequencing of Plasma for Diagnosis of COVID-19-Associated Pulmonary Aspergillosis
Journal of Clinical Microbiology (February 2023)
The effect of a plasma next-generation sequencing test on antimicrobial management in immunocompetent and immunocompromised patients - A single-center retrospective study
Cambridge University Press (February 2023)
Metagenomics in infectious disease diagnostics: Toward best-use practices to optimize actionable results
Transplant Infectious Disease (December 2022)
Cell-free next-generation sequencing impacts diagnosis and antimicrobial therapy in immunocompromised hosts: A retrospective study
Transplant Infectious Disease (January 2023)
Budget Impact of Microbial Cell-Free DNA Testing Using the Karius Test as an Alternative to Invasive Procedures in Immunocompromised Patients with Suspected Invasive Fungal Infections
Applied Health Economics and Health Policy (September 2020)
Plasma Microbial Cell-free DNA Next Generation Sequencing in the Diagnosis and Management of Febrile Neutropenia
Infectious Diseases Society of America (April 2021)
Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious diseases (SEP-SEQ, Nature Paper)
Nature Microbiology (February 2019)
The role of plasma metagenomic sequencing in identification of Balamuthia mandrillaris encephalitis
Acta Neuropathologica Communications (March 2025)
Illuminating the Challenges and Diagnostic Utility of Plasma Microbial Cell-Free DNA Sequencing in Suspected Infective Endocarditis: A Retrospective Observational Cohort Study
Open Forum Infectious Diseases (February 2025)
Plasma Microbial Cell-free DNA Sequencing for the Detection of Kingella kingae Pediatric Spinal Infections
The Pediatric Infectious Disease Journal (February 2025)
Chorioretinitis following Bacillus Calmette-Guerin Treatment for Bladder Cancer
Retinal Cases & Brief Reports (February 2025)
Quantitative Microbial Cell-Free DNA Sequencing From Plasma: A Potential Biomarker for the Diagnosis of Staphylococcal Infection of Cardiac Implantable Electronic Devices
Clinical Infectious Diseases (March 2025)
The cruciality of increasing index of suspicion for atypical Bartonella henselae in pediatric patients: A case series
IDCases (March 2025)
Mycobacterium haemophilum diagnosed via Karius test in a heart transplant recipient: A case report
Transplant Immunology (May 2025)
Bartonella quintana Endocarditis and Pauci-Immune Glomerulonephritis in Patient without Known Risk Factors, USA, 2024
Emerging Infectious Diseases (April 2025)
Plasma Microbial Cell-free DNA Metagenomic Sequencing for Diagnosis of Invasive Fungal Diseases Among High-risk Outpatient and Inpatient Immunocompromised Hosts
Clinical Infectious Diseases (April 2025)
Aortic Endograft infection with Mycobacterium bovis following intravesical BCG immunotherapy diagnosed via The Karius Test™- Case Report and review of literature
Annals of Vascular Surgery - Brief Reports and Innovations (March 2025)