Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study
The Lancet Microbe (March 2026)
Clinical Data
Clinical Study
Lancet Microbe 2026
Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study
Some of the publications and abstracts listed on this page may reference the Karius Spectrum test under it's former name Karius Test. This product was rebranded to Karius Spectrum as of March 17, 2025.
Key Publications
Plasma Microbial Cell-Free DNA Sequencing in Immunocompromised Patients with Pneumonia: A Prospective Observational Study
Clinical Infectious Diseases (October 2023)
Metagenomic Next-Generation Sequencing of Plasma for Diagnosis of COVID-19-Associated Pulmonary Aspergillosis
Journal of Clinical Microbiology (February 2023)
Metagenomics in infectious disease diagnostics: Toward best-use practices to optimize actionable results
Transplant Infectious Disease (December 2022)
Cell-free next-generation sequencing impacts diagnosis and antimicrobial therapy in immunocompromised hosts: A retrospective study
Transplant Infectious Disease (January 2023)
Budget Impact of Microbial Cell-Free DNA Testing Using the Karius Test as an Alternative to Invasive Procedures in Immunocompromised Patients with Suspected Invasive Fungal Infections
Applied Health Economics and Health Policy (September 2020)
Plasma Microbial Cell-free DNA Next Generation Sequencing in the Diagnosis and Management of Febrile Neutropenia
Infectious Diseases Society of America (April 2021)
Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious diseases (SEP-SEQ, Nature Paper)
Nature Microbiology (February 2019)
A Presentation of Necrotizing Disseminated Sporotrichosis
Cureus (February 2026)
Kingella kingae Endocarditis and Septic Pulmonary Emboli in a 12-Year-Old Male With Repaired Tetralogy of Fallot and a Bioprosthetic Pulmonary Valve
Case Reports in Cardiology (February 2026)
Disseminated Fungal Infection in Profoundly Immunocompromised Hosts: A Three-Case Series
Cureus (February 2026)
Pre- and peri-hematopoietic cell transplant management of disseminated non-Helicobacter pylori Helicobacter infection in X-linked agammaglobulinemia: Case series and literature review
Clinical Immunology (February 2026)
A 2-Month-Old With Unusual Tachypnea
Clinical Pediatrics (February 2026)
Anti-GAD Autoimmune Encephalitis Following Primate Bocaparvovirus 2 Infection in an Immunocompromised Host: A Case Report and Review of the Literature
Infectious Disease in Clinical Practice (February 2026)
Comparative study of plasma microbial cell-free DNA sequencing to culture and polymerase chain reaction in pediatric community-acquired pneumonia with parapneumonic effusion or empyema
Journal of Clinical Microbiology (February 2026)
Case Series: Use of Dalbavancin for Invasive Gram-Positive Infection in Children
Journal of Pediatric Pharmacology and Therapeutics (February 2026)
Microbial lung-to-blood translocation associates with systemic inflammation in severe pneumonia: evidence from paired plasma and lower respiratory tract metagenomics
Intensive Care Medicine Experimental (February 2026)
Disseminated Histoplasmosis and Aortic Valve Infective Endocarditis in a Patient With Recent Aortobifemoral Bypass
American Journal of Case Reports (January 2026)