Plasma Microbial Cell-Free DNA Sequencing in Immunocompromised Patients with Pneumonia: A Prospective Observational Study
Clinical Infectious Diseases (October 2023)
Clinical Data
Clinical Study
Therapeutic Advances in Infectious Disease
Clinical utility of plasma microbial cell-free DNA sequencing in determining microbiologic etiology of infectious syndromes in solid organ transplant recipients
Some of the publications and abstracts listed on this page may reference the Karius Spectrum test under it's former name Karius Test. This product was rebranded to Karius Spectrum as of March 17, 2025.
Key Publications
Metagenomic Next-Generation Sequencing of Plasma for Diagnosis of COVID-19-Associated Pulmonary Aspergillosis
Journal of Clinical Microbiology (February 2023)
The effect of a plasma next-generation sequencing test on antimicrobial management in immunocompetent and immunocompromised patients - A single-center retrospective study
Cambridge University Press (February 2023)
Metagenomics in infectious disease diagnostics: Toward best-use practices to optimize actionable results
Transplant Infectious Disease (December 2022)
Cell-free next-generation sequencing impacts diagnosis and antimicrobial therapy in immunocompromised hosts: A retrospective study
Transplant Infectious Disease (January 2023)
Budget Impact of Microbial Cell-Free DNA Testing Using the Karius Test as an Alternative to Invasive Procedures in Immunocompromised Patients with Suspected Invasive Fungal Infections
Applied Health Economics and Health Policy (September 2020)
Plasma Microbial Cell-free DNA Next Generation Sequencing in the Diagnosis and Management of Febrile Neutropenia
Infectious Diseases Society of America (April 2021)
Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious diseases (SEP-SEQ, Nature Paper)
Nature Microbiology (February 2019)
Ophthalmic Vein Thrombosis, Abducens Nerve Palsy, and Horner Syndrome Secondary to Lemierre Syndrome
Ophthalmic Vein Thrombosis, Abducens Nerve Palsy, and Horner Syndrome Secondary to Lemierre Syndrome (July 2025)
Implantable cardioverter-defibrillator infection by Streptococcus intermedius identified by next-generation sequencing
Journal of case Reports and Images in Infectious Diseases (June 2025)
Whipple’s endocarditis diagnosed non-invasively with plasma microbial cell-free DNA sequencing
ID Cases (July 2025)
A case of pneumococcal periaortitis: periaortitis is not always autoimmune
European Journal of Case Reports in Internal Medicine (July 2025)
Brain Abscess Complicating Metastatic Scalp Basal Cell Carcinoma With a Malignant Fungating Wound
July 2025
Mycoplasma hominis prosthetic valve infective endocarditis and endophthalmitis in a renal transplant recipien
Therapeutic Advances in Infectious Disease (July 2025)
Capnocytophaga Meningitis: A Rare Case of Bacterial Infection With Neurological Manifestation
Cureus (December 2024)
Concurrent Zoster Sine Herpete and Hepatosplenic Fungal Infection in a Cancer Patient
Cureus (October 2024)
Fever of Unknown Origin in a Young Woman With Multiple Comorbidities: A Diagnostic Challenge
Cureus (February 2025)
Mycobacterium immunogenum-Induced Thrombocytopenia
Cureus (January 2025)