
Detecting Microbes
That Impact Human Health.
By leveraging the power of clinical metagenomics, our vision is to create a world where every patient gets a clear and timely diagnosis.

Detecting Microbes
That Impact Human Health.
By leveraging the power of clinical metagenomics, our vision is to create a world where every patient gets a clear and timely diagnosis.
We use genomics and AI to advance infectious disease diagnostics.
Microbial Cell-Free DNA
Karius provides unique genomic insights by detecting microbial cell-free DNA (mcfDNA) circulating throughout the body from pathogens that may cause infections.
AI Technology
Advanced machine learning algorithms allow analysis of complex genomic data in real time. Our proprietary reference genome databases are constantly refined as more data becomes available.
Explore Our Solution
Karius is transforming infectious disease diagnostics with metagenomic sequencing tests that give providers rapid and comprehensive detection of pathogens behind life-threatening infections when conventional testing falls short.

Karius SpectrumTM
Karius SpectrumTM is a blood test leveraging plasma metagenomic sequencing of microbial cell-free DNA to detect over 1,000 fungi, bacteria, DNA viruses, and parasites associated with deep-seated and difficult-to-diagnose systemic infections.

Karius FocusTM | BAL
Karius Focus™ | BAL is a bronchoalveolar lavage fluid-based mcfDNA metagenomic sequencing test that is designed for detection and classification of over 500 pathogens associated with lung infection.
Latest News & Updates

Pulmonary Precision: Karius Launches Metagenomic Test for Lung Infections
Karius, a leader in metagenomic sequencing for infectious disease diagnostics, unveiled its latest breakthrough: the “Karius Focus | BAL” microbial cell-free DNA (cfDNA) test. This diagnostic tool uses bronchoalveolar lavage (BAL) samples to support clinical identification of pathogens causing pneumonia and other lung infections, particularly in immunocompromised patients.
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Karius, Inc. Announces Collaboration to Extend Access to Infectious Disease Diagnostics
REDWOOD CITY, Calif., April 23, 2026 – Karius, Inc. (“Karius”) and Mayo Clinic Laboratories today announced a collaboration to make Karius’s advanced metagenomic infectious disease diagnostic offerings, the Karius Spectrum™ and the Karius Focus™ | BAL tests, available to order through Mayo Clinic Laboratories.
Learn MoreKarius is a 2026 Top Workplace
Top Workplaces Regional Awards by the San Francisco Chronicle for the past three years and running.
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