Karius

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Karius is your partner in diagnosing infections.

By providing healthcare providers a non-invasive and comprehensive blood test to diagnose infections –
we are here to help. 

How We Help

 

Genomic Insights for Infectious Diseases

 

The Karius® Test is a blood test based on next-generation sequencing of microbial cell-free DNA. It can identify and quantify over 1,000 clinically relevant pathogens including bacteria, DNA viruses, fungi, and parasites. Applications include complicated pneumonia, infections in immunocompromised patients, and endocarditis.

 

Karius® Test

 

We use genomics and AI to advance infectious disease diagnostics.

 

 

 

Microbial cell-free DNA

Karius provides unique genomic insights by detecting microbial cell-free DNA (mcfDNA) circulating in the bloodstream from pathogens causing an acute infection. Proprietary technology efficiently extracts mcfDNA directly from blood and depletes the strong human background signal and environmental contaminants.

 

 

 
Karius AI technology

Advanced machine learning algorithms allow analysis of complex genomic data in real-time. Proprietary reference genome databases are constantly refined as more data becomes available.

 

 

Ryan Visits Karius Headquarters

"That's really what it's all about. Trying to figure out what people have in time to save them."

Ryan S

Patient was reimbursed for travel and expenses related to the video shoot.  

 

Brian's story

"The Karius Test saved my life by identifying the deadly strain of bacteria (Fusobacterium) that caused my life-threatening pneumonia."

 

Brian J
Read his full story here

Patient was reimbursed for travel and expenses related to the video shoot.  

Over 1,000 clinically relevant bacteria, DNA viruses, fungi, and pathogens detected by the Karius Test with a single blood draw.

750+

Bacteria detected

Highlighted Bacteria:

Nocardia species (67)
Legionella species (30)
Rickettsia species (17)
Actinomyces species (15)
Mycoplasma species (8)
HACEK organisms (including Aggregatibacter actinomycetemcomitans,
Aggregatibacter aphrophilus,
Aggregatibacter segnis,
Cardiobacterium hominis,
Eikenella corrodens,
Haemophilus aegyptius,
Haemophilus parainfluenzae,
Kingella denitrificans and
Kingella kingae)
Streptobacillus moniliformis
Mycobacterium tuberculosis complex
Mycobacterium avium complex (MAC)
Mycobacterium chimaera

Published studies demonstrate the clinical impact of the Karius Test.

 

 

 

10+ publications

40+ abstracts

10+ clinical trials

 

 

 

Clinical Data

 

 

The latest from Karius

 

 

References:

1. Fauci AS. et al, Emerging Infect Dis. 2005 Apr;11(4):519-25
2. Jain et al, NEJM. 2015 Dec 10;373(24):2382.
3. Gupta S. et al, Chest. 2016; 150:1251-1259