Plasma Microbial Cell-Free DNA Sequencing in Immunocompromised Patients with Pneumonia: A Prospective Observational Study
Clinical Infectious Diseases (October 2023)
Clinical Data
Clinical Study
Antimicrobial Stewardship & Healthcare Epidemiology
The effect of a plasma next-generation sequencing test on antimicrobial management in immunocompetent and immunocompromised patients—A single-center retrospective study
Some of the publications and abstracts listed on this page may reference the Karius Spectrum test under it's former name Karius Test. This product was rebranded to Karius Spectrum as of March 17, 2025.
Key Publications
Metagenomic Next-Generation Sequencing of Plasma for Diagnosis of COVID-19-Associated Pulmonary Aspergillosis
Journal of Clinical Microbiology (February 2023)
The effect of a plasma next-generation sequencing test on antimicrobial management in immunocompetent and immunocompromised patients - A single-center retrospective study
Cambridge University Press (February 2023)
Metagenomics in infectious disease diagnostics: Toward best-use practices to optimize actionable results
Transplant Infectious Disease (December 2022)
Cell-free next-generation sequencing impacts diagnosis and antimicrobial therapy in immunocompromised hosts: A retrospective study
Transplant Infectious Disease (January 2023)
Budget Impact of Microbial Cell-Free DNA Testing Using the Karius Test as an Alternative to Invasive Procedures in Immunocompromised Patients with Suspected Invasive Fungal Infections
Applied Health Economics and Health Policy (September 2020)
Plasma Microbial Cell-free DNA Next Generation Sequencing in the Diagnosis and Management of Febrile Neutropenia
Infectious Diseases Society of America (April 2021)
Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious diseases (SEP-SEQ, Nature Paper)
Nature Microbiology (February 2019)
Case of Congenital Tularemia with Neuroinvasive Disease, Utah, USA
Emerging Infectious Diseases (December 2025)
Bartonella Endocarditis in a Pediatric Patient With Aortic Valvular Disease and Embolic Stroke: A Case Report and Review of the Literature
Cureus Journal of Medical Science (December 2025)
Aspergillus calidoustus: An Emerging Cause of Invasive Aspergillosis and the Role of Metagenomic Next-Generation Sequencing Test in Its Diagnosis
Case Reports in Infectious Disease (November 2025)
In-matrix library preparation for metagenomic sequencing of microbial cell-free DNA
Journal of Clinical Microbiology (November 2025)
Enterohepatic Non-H. pylori Helicobacter Infection in a Patient With X-Linked Agammaglobulinemia
Pediatric Dermatology (November 2025)
Case Report: A fatal case of CNS actinomycosis mimicking Tolosa–Hunt syndrome: Is it time to reevaluate diagnostic criteria?
Frontiers In Medicine (September 2025)
Microbial Cell-Free DNA Sequencing in the Identification of Rhizopus Arrhizus in an Adolescent With Gastrointestinal Mucormycosis
Cureus Journal of Medical Science (November 2025)
Invasive Conidiobolus infection in an immunocompromised pediatric patient in Southern California
ASM Case Reports (November 2025)
Prostatic Abscess due to Ureaplasma parvum in a Heart Transplant Recipient: Diagnostic Challenges and Clinical Utility of Metagenomics Next‐Generation Sequencing (NGS)
Case Report in Infectious Diseases (November 2025)
Application of plasma cell-free metagenomic next-generation sequencing for the identification of Aspergillus fumigatus donor-derived infections among solid organ transplant recipients
Medical Mycology Case Reports (December 2025)