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We are here to support you during the COVID-19 pandemic.

Karius is your partner in diagnosing infections.

How We Help


Genomic Insights for Infectious Diseases


The Karius® Test is a blood test based on next-generation sequencing of microbial cell-free DNA. It can identify and quantify over 1,000 clinically relevant pathogens including bacteria, DNA viruses, fungi, and parasites. Applications include complicated pneumonia, infections in immunocompromised patients, and endocarditis.


Karius® Test


We use genomics and AI to advance infectious disease diagnostics.




Microbial cell-free DNA

Karius provides unique genomic insights by detecting microbial cell-free DNA (mcfDNA) circulating in the bloodstream from pathogens causing an acute infection. Proprietary technology efficiently extracts mcfDNA directly from blood and depletes the strong human background signal and environmental contaminants.



Karius AI technology

Advanced machine learning algorithms allow analysis of complex genomic data in real-time. Proprietary reference genome databases are constantly refined as more data becomes available.





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AI 50

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UCSF Digital Health Awards
New Application of AI

Forbes AI 50 Award Badge


CB Insights
Digital Health 150



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Clinical OMICs
Precision Medicine Companies Making Their Mark in 2020



Ryan Visits Karius Headquarters

"That's really what it's all about. Trying to figure out what people have in time to save them."

Ryan S

Patient was reimbursed for travel and expenses related to the video shoot.  



The latest from Karius

Over 1,000 clinically relevant bacteria, DNA viruses, fungi, and pathogens detected by the Karius Test with a single blood draw.


Bacteria detected

Highlighted Bacteria:

Nocardia species (72)
Legionella species (42)
Rickettsia species (18)
Actinomyces species (15)
Mycoplasma species (12)
HACEK organisms (including Aggregatibacter actinomycetemcomitans,
Aggregatibacter aphrophilus,
Aggregatibacter segnis,
Cardiobacterium hominis,
Eikenella corrodens,
Haemophilus aegyptius,
Haemophilus parainfluenzae,
Kingella denitrificans and
Kingella kingae)
Streptobacillus moniliformis
Mycobacterium tuberculosis complex
Mycobacterium avium complex (MAC)
Mycobacterium chimaera

Published studies demonstrate the clinical impact of the Karius Test.




40+ publications

70+ abstracts

10+ clinical trials




Clinical Data






1. Fauci AS. et al, Emerging Infect Dis. 2005 Apr;11(4):519-25
2. Jain et al, NEJM. 2015 Dec 10;373(24):2382.
3. Gupta S. et al, Chest. 2016; 150:1251-1259