Karius at IDWeek 2018 | Karius

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Karius Abstracts at IDWeek 2018

At Karius, we are focused on helping clinicians diagnose infections and guide treatment for their patients.

At IDWeek 2018, Karius presented 7 abstracts. You can see a full list and download summaries and posters below.

Please contact us for more information on how the Karius Test can apply to your institution.

IDWeek 2018, San Francisco, October 3-7, 2018

Karius presented 7 abstracts and hosted a learning lounge


The Karius® NGS Test: Liquid Biopsy for Infectious Diseases

The Karius Test can detect over 1,000 pathogens from a single non-invasive blood draw, including bacteria, DNA viruses, fungi, and protozoa. Hear physicians describe cases of using the Karius Test for patients with encephalitis, invasive fungal infections, pneumonia, and other diagnostically challenging conditions.

-David K. Hong, MD, Karius
-Christopher D. Cooper, MD, Florida Hospital
-Kenneth H. Rand, MD, University of Florida
-William J. Muller, MD, PhD, Ann & Robert H. Lurie Children’s Hospital





Evaluation of the Karius Plasma Next Generation Sequencing Cell-free Pathogen DNA Test to Determine the Etiology of Infection and Impact on Anti-Microbial Management in Patients with Severe Neutropenia and Fever

Tags: IDWeek 2018, immunocompromised, febrile neutropenia

Summary: The Karius Test can provide fast and accurate detection of pathogens and clinically relevant polymicrobial infections in febrile neutropenic patients which can inform treatment decisions.

View Abstract or Download PDF (1.1 MB)


Plasma Next-Generation Sequencing for Pathogen Detection in Pediatric Patients at Risk for Invasive Fungal Infection

Tags: IDWeek 2018, immunocompromised, fungal

Summary: The Karius Test can detect invasive fungal infections (IFI) directly from blood in high-risk pediatric immunocompromised patients and can identify non-fungal pathogens in individuals that have prolonged febrile neutropenia but do not meet criteria for proven or probable IFI.

View Abstract or Download PDF (6.3 MB)


Prediction of Bloodstream Infection Prior to Onset of Symptoms by Plasma Metagenomic Sequencing in Pediatric Patients with Relapsed or Refractory Malignancy (PREDSEQ)

Tags: IDWeek 2018, pediatric, immunocompromised

Summary: The Karius Test identified bloodstream infections prior to the onset of clinical symptoms in high-risk pediatric cancer patients.

View Abstract or Download PDF (144 KB)


Diagnosis of BCG Aortitis Aided by Plasma Metagenomic Sequencing

Tags: IDWeek 2018, aortitis

Summary: The use of the Karius Test allowed for non-invasive diagnosis of BCG-associated endovascular infection in a patient much faster than AFB cultures and PCR.

View Abstract or Download PDF (743 KB)


Direct Detection and Quantification of Bacterial Cell-free DNA in Patients with Infective Endocarditis Using the Karius Plasma Next Generation Sequencing Test

Tags: IDWeek 2018, endocarditis

Summary: The Karius Test, with its ability to detect and quantitate a wide breadth of pathogens, can be a useful diagnostic and monitoring tool for infective endocarditis, even in patients with culture-negative endocarditis.

View Abstract or Download PDF (146 KB)


Streptococcus pneumoniae-related hemolytic uremic syndrome (pHUS) and the identification of matched cross-country serotypes by plasma next-generation sequencing (NGS)

Tags: IDWeek 2018, pneumonia

Summary: The Karius Test can detect culture-negative infections and has the potential to identify clusters of disease.

View Abstract or Download PDF(3.2 MB)


Diagnosis and Genotyping of Coxiella burnetii Causing Endocarditis in a Patient with Prosthetic Pulmonary Valve Replacement Using Next-Generation Sequencing of Plasma

Tags: IDWeek 2018, endocarditis

Summary: The Karius Test enabled earlier diagnosis of Coxiella burnettii culture-negative endocarditis (Q Fever) leading to early targeted antimicrobial therapy.

View Abstract or Download PDF(146 KB)

To learn more about the test and how it can help your patients, please email medical@kariusdx.com to schedule time with our Medical Directors.

We look forward to talking to you.