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Karius ASM Industry Showcase Webinar: Clinical Application of a Plasma Next-Generation Sequencing Test for Pathogen Detection


This talk was recorded at the ASM Microbe 2018 meeting on Saturday, June 9, 2018 in Atlanta, GA.

Clinical Application of a Plasma Next-Generation Sequencing Test for Pathogen Detection

Introduction to the Karius Test
Tim Blauwkamp, PhD, Chief Scientific Officer, Karius

The SEP-SEQ Trial: Clinical Validation of the Karius Test in Sepsis
Simone Thair, PhD, Stanford University 

Clinical Experience with the Karius Test at Children’s National Medical Center
Joseph M. Campos, PhD, D(ABMM), Children's National Medical Center 

Clinical Applications of the Karius Test
David K. Hong, MD, VP Medical Affairs and Clinical Development, Karius
Current infectious disease testing methods such as blood cultures and PCR panels offer limited diagnostic capability. Many tests only detect a single pathogen or a small panel of pathogens, or cannot detect fastidious and unculturable organisms.  Deep-seated infections may require an invasive biopsy and uncommon pathogens can often be missed. 
Applying next-generation sequencing (NGS) of microbial cell-free DNA to pathogen detection holds great promise for transforming our current diagnostic methods to a more comprehensive molecular approach.  
The Karius™ Test is a plasma-based NGS assay designed to rapidly and precisely detect over 1,000 pathogens, including bacteria, fungi, protozoa, and DNA viruses.  The test can identify pathogens in culture-negative infections including sepsis, and in deep infections often requiring invasive biopsy such as invasive fungal infections. 
This session highlights the clinical experience of utilizing the Karius Plasma NGS test, the results from the SEP-SEQ Trial for sepsis, and clinical applications of the Karius Test in various medical settings to detect a variety of difficult-to-diagnose pathogens that impact clinical outcomes. 

For information on how to order the Karius Test at your institution, please sign up for our newsletter here, email us at info@kariusdx.com, or call 1-866-452-7487.

To register for our next webinar on Invasive Fungal Infections, please click here

More webinars:

Introduction and Clinical Experience with the Karius Test