Staff Scientist, Automation | Karius

Staff Scientist, Automation

About Karius
Karius is a venture-backed life science startup that is transforming the way pathogens and other microbes are observed throughout the body.  By unlocking the information present in microbial cell-free DNA, we're helping doctors quickly solve their most challenging cases, providing industry partners with access to 1000’s of biomarkers to accelerate clinical trials, discovering new microbes, and reducing patient suffering worldwide.
Position Summary
As a Staff Scientist, Automation you will work alongside other scientific leaders in NGS-based infectious disease diagnostics providing meaningful contributions to making an impact in the lives of patients while contributing to the company’s growth and development. You will be responsible for maintaining and supporting process excellence for a state-of-the art NGS infectious disease diagnostic assay. You will lead the automation development related to several exciting research projects and be at the forefront of non-invasive diagnostics working alongside our scientists to develop new automated processes. The ideal candidate should have experience working with Hamilton automated liquid handlers in a regulated environment.

Why Should You Join Us?
Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions. The Karius test we provide today is one of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients. Our test is the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission. You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale.
Reports to: Director, Research
Location: Redwood City, CA
Primary Responsibilities
•  Participate in the design and development of the automation strategy.
•  Drive projects and coordinate cross-functionally to ensure successful project execution and meeting deliverables on time and within budget.
•  Design and analyze the necessary experiments of high complexity to test the performance of the automated workflows.
•  Prepare presentations and present experimental data to research team or broader.
•  Interface with lab automation suppliers and part-take in strategic negotiations.
•  Supervise junior automation scientists.
•  Conduct manufacturing and experimental processes according to established SOPs. 
•  Support of the automated CLIA diagnostic processes.
•  Work comfortably in a fast-paced, collaborative, startup environment.
•  May be required to perform other duties as assigned.

What’s Fun About the Job?
Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters.
Travel: No travel required.
Physical Requirements
Subject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels. 
Position Requirements
•  Ph.D. (or Master's degree) in Biology, Molecular Biology, Genetics or related field.
•  A minimum of 8 years of industry related laboratory experience.
•  Proven record of critical thinking, attention to detail, good presentation skills, and thorough record-keeping.
•  Proficient in scripting Hamilton STAR automated liquid handlers
•  Experienced with equipment and processes used in NGS diagnostics (PCR thermocyclers, extraction, library generation etc.).
•  Proficient in use of Microsoft Office Excel and Word.
Preferred Requirements
•  Experience with molecular biology process, e.g. DNA/RNA purification.
•  Experience with NGS library processes and data processing.
Personal Requirements
•  Ability to work independently and collaboratively with team members.
•  Highly goal-driven and have demonstrated the ability to effectively prioritize and focus on time-sensitive objectives.
•  Strong problem-solving and troubleshooting skills.
•  Excellent teamwork and motivation skills are essential.
•  Excellent organizational, record-keeping and communication (verbal and written) skills.
•  Strong work ethic to generate high quality work under tight deadlines.
At Karius, we value a diverse and inclusive workplace and provide equal employment opportunity for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company.  All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at and we will accommodate qualified individuals with disabilities.

Redwood City, CA