Sr. Software Engineer (Analytics) | Karius

Sr. Software Engineer (Analytics)

About Karius
Karius is a venture-backed life science startup that is transforming the way pathogens and other microbes are observed throughout the body. By unlocking the information present in microbial cell-free DNA, we're helping doctors quickly solve their most challenging cases, providing industry partners with access to 1000’s of biomarkers to accelerate clinical trials, discovering new microbes, and reducing patient suffering worldwide. 

Position Summary
We are building and operating a unique software stack of cloud infrastructure, software services, APIs, web and mobile interactive interfaces, and AI-driven data analytics pipelines to deliver life-saving results in the highly complex infectious disease landscape. We believe the success of Karius’ products is driven by both our unique technology and the elegance of the software solution. We seek talented and passionate individuals who want to be part of this impactful journey reaching the team’s ambitious goals, far beyond what any single individual could accomplish. As a Sr. Software Engineer in this space, your primary focus will be developing and maintaining software and infrastructure to execute Karius diagnostic analytical pipeline in commercial and research setup. 

Why Should You Join Karius?
Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions. The Karius test we provide today is one of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients. Our test is the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission. You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale. 

Reports to: VP, Engineering  

Location: Redwood City, CA 

Primary Responsibilities 
•  In collaboration with the scientific and analytical teams, understand Karius diagnostic analytical processes and articulate the requirements and roadmap to achieve business objectives.
•  Deliver a platform and a tool-chest to accelerate the pace of R&D innovation via experimenting with new ideas.
•  In collaboration with the engineering team, streamline the development, testing and validation of analytical pipelines to reduce the cost and lead time for releasing new features to production. This includes designing, developing, testing, and supporting full-stack solutions in a cloud environment.
•  Contribute to advancing a culture of a high-performing team by having close collaboration and engagement with the rest of the engineering team in solving technical challenges as they arise. 

What’s Fun About the Job?
Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters.

Travel: No travel required.    

Physical Requirements 
Subject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels. Work is generally performed in an office environment.  

Position Requirements
First and foremost, you are energized and motivated by the opportunity to build an elegant software. You enjoy seeing your creation work like a clock positively impacting thousands of people every year. You crave tough challenges in a super technical and collaborative environment that requires creativity and vision to navigate complex and ambiguous problems.  

In addition, you will be able to present: 
•  BS or MS degree in Computer Science, Software Engineering, Electrical Engineering, Bio Engineering or related technical fields involving algorithms or coding (e.g., physics or mathematics) 
•  5+ years of software engineering experience, including designing, developing and maintaining full stack solutions in a production environment.  
•  Advanced knowledge and 3+ years of experience implementing production software using Python.

Knowledge and hands on experience with:
•  Implementing DAGs using workflow engines such as Apache Airflow, Argo and SGE. Workload resource management technologies such as Apache Mesos and Kubernetes, and containerized software deployment using Docker.
•  Data modeling and servicing through APIs such as REST and GraphQL.
•  A set of highly desired knowledge and experiences: Building and supporting bioinformatics analytical pipeline. 
•  Next-generation sequencing (NGS) data generation and processing from raw sequencing reads to biological insight.
•  Experience in experimental data analysis, statistical methods, and visualization. 

Personal Qualifications 
•  Passionate, purpose-driven, and excited about Karius’ mission.
•  Mastered your craft yet eager to learn and grow.
•  Demonstrated ability to tackle complex problems.
•  Ability to work independently but also be an excellent team player.
•  Ability to work effectively and efficiently in a fast paced (startup) environment. 

At Karius, we value a diverse and inclusive workplace and provide equal employment opportunity for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company.  All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at and we will accommodate qualified individuals with disabilities.

Redwood City, CA