Sr. Manager, Health Economics and Outcomes Research | Karius

Sr. Manager, Health Economics and Outcomes Research

About Karius
Karius is a venture-backed life science startup that is transforming the way pathogens and other microbes are observed throughout the body.  By unlocking the information present in microbial cell-free DNA, we're helping doctors quickly solve their most challenging cases, providing industry partners with access to 1000’s of biomarkers to accelerate clinical trials, discovering new microbes, and reducing patient suffering worldwide.

Position Summary
Karius is searching for a Sr. Manager, Health Economics and Outcomes Research to join our newly formed Clinical Data Science team. We are looking for an experienced health economist who is passionate about improving patient care through rigorous analysis of observational data (cost effectiveness analyses, budget impact models, and observational causal statistics).

As a Sr. Manager, Health Economics and Outcomes Research, you will be responsible for leading the quality and timely delivery of projects, including strategy, methods, and stakeholder management. You will collaborate cross-functionally with Clinical Development, Scientific Discovery, Commercial Affairs, and Analytics to develop and carry out rigorous evaluations of HEOR hypotheses using molecular, claims, and electronic health record data. You will also identify opportunities for research projects that increase knowledge about the impact of microbial cell free DNA testing on human health.

Why Should You Join Karius?
Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions. The Karius test we provide today is one of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients. Our test is the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission. You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale.

Reports to:  Director, Clinical Data Science

Location:  Redwood City, CA

Primary Responsibilities
•  With support from the Director, leads and manages projects and resources in the execution of HEOR studies, including initiating projects, overseeing execution, performing quality review, and leading cross-team communications
•  Designs and carries out research studies intended to evaluate health economic and clinical outcomes hypotheses using established and innovative statistical and econometric methods
•  Advises on study protocols, statistical analyses or other project implementation plans in collaboration with clinical development, scientific discovery, commercial, and product teams to address research questions and objectives
•  Identifies appropriate data and data schemas from literature and databases (open-access, government, commercial)Produces technical reports, peer-reviewed manuscripts, and presentations

What’s Fun About the Job?
Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters. 

Travel:  No travel required. 

Physical Requirements 
Subject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels. Work is generally performed in an office environment.

Position Requirements
•  Master’s degree or Ph.D. in a discipline related to health services research: economics, public policy, health policy, epidemiology, biostatistics, statistics, or public health.
•  A minimum 4 years of relevant research experience.
•  Experience with a variety of HEOR methods:
   - Cost effectiveness analyses
      - Budget impact models
      - Value-based pricing
      - Survival/competing risks models
      - Marginal structural models
      - Bayesian proportional odds 
•  Knowledge of the US healthcare system, including diagnostic testing regulations (laboratory developed test and in vitro devices), payer reimbursement decisions, hospital billing processes, etc. 
•  Technical ownership within a consulting organization, academia, or industry.
•  Experience leading health economics and outcomes research projects to completion, preferred.

Personal Qualifications 
•  Passionate, purpose-driven, and excited about Karius’ mission.
•  Mastered your craft, eager to learn and grow and desire to share knowledge.
•  Detail oriented with exceptional organizational and time management skills.
•  Ability to work independently but also be an excellent team player.
•  Ability to work effectively and efficiently in a fast paced (startup) environment.
•  Superior communication and analytical skills, including strong ability to identify and solve ambiguous and complex problems.

Redwood City, CA