Sr. Manager, Biostatistics | Karius

Sr. Manager, Biostatistics

About Karius
Karius is a venture-backed life science startup that is transforming the way pathogens and other microbes are observed throughout the body.  By unlocking the information present in microbial cell-free DNA, we're helping doctors quickly solve their most challenging cases, providing industry partners with access to 1000’s of biomarkers to accelerate clinical trials, discovering new microbes, and reducing patient suffering worldwide. 

Position Summary
Karius is searching for a Sr. Manager, Biostatistics to join our newly formed Clinical Data Science team. We are looking for an experienced biostatistician who is passionate about using data from observational (retrospective and prospective) and interventional studies to further our knowledge of the interaction between human health and microbial cell free DNA.

As a Sr. Manager, Biostatistics you will ensure the timely delivery of quantitative projects, including strategy, methods, quality, and stakeholder management. You will collaborate with Clinical Development, Scientific Discovery, Commercial Affairs, and Analytics to develop and carry out rigorous evaluations of scientific hypotheses using clinical, administrative, and molecular data.

Why Should You Join Us?
Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions. The Karius test we provide today is one of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients. Our test is the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission. You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale.

Reports to:    Director, Clinical Data Science

Location:    Redwood City, CA

Primary Responsibilities
•  In partnership with the Director, Clinical Data Science, lead and manage projects and resources in the execution of statistical analyses of clinical and molecular data including initiating projects, overseeing execution, performing quality review, and leading cross-team communications.
•  Designs research studies intended to address clinical biomarker and health economic outcomes research using a range of statistical methods.
•  Advises on study protocols, statistical analysis or other project implementation plans in collaboration with clinical development, scientific discovery, commercial, and product teams to address research questions and objectives.
•  Identifies and advises on appropriate data including from literature, databases, interviews and/or surveys using scientifically valid methods.
•  Advises quality assurance and quality control procedures.
•  Produces technical reports, peer-reviewed manuscripts, and presentations.

What’s Fun About the Job?
Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters.

Travel:  No travel required.

Physical Requirements 
Subject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels. Work is generally performed in an office environment.

Position Requirements
•  Master’s degree in a discipline related to biostatistics: statistics, epidemiology, biostatistics, public health, computational biology, applied math, or genomics.
•  A minimum 4 years of relevant research experience.
•  Knowledge of biomedicine, with additional expertise in diagnostic testing and/or infectious diseases, preferred.
•  Technical ownership within a consulting organization, academia, or industry.
•  Deep understanding of the application of biostatistical methods (e.g modeling, observational research, statistical programming), preferred.
•  Experience leading quantitative research projects to completion, preferred.

Personal Qualifications
•  Passionate, purpose-driven, and excited about Karius’ mission.
•  Mastered your craft, eager to learn and grow and desire to share knowledge.
•  Detail oriented with exceptional organizational and time management skills.
•  Ability to work independently but also be an excellent team player.
•  Ability to work effectively and efficiently in a fast paced (startup) environment.
•  Superior communication and analytical skills, including strong ability to identify and solve ambiguous and complex problems.

Redwood City, CA