Scientist | Karius

Scientist

Karius is a venture-backed life science startup focused on transforming the way infectious diseases are diagnosed.  Combining Next-Generation Sequencing and proprietary data analysis, we can identify over 1,000 pathogens from a single blood sample with typical turnaround time in one business day. By unlocking the information present in microbial cell-free DNA, we're helping doctors quickly solve their most challenging cases, with a future vision of accelerating clinical trials, discovering new microbes, and reducing patient suffering worldwide.
 
Position Summary
We are looking for an extraordinary scientist to develop NGS-based clinical diagnostic assays into robust clinical products. The ideal candidate will design and execute superior assay development plans, optimize assays for astounding efficiency and robustness, identify in-line quality control measures that ensure industry-leading data integrity.  If you are highly experienced in developing novel diagnostic approaches for nucleic acid detection as well as assay optimization, have worked extensively with NGS workflows and are eager to do the best work of your life, we should talk!
 
Reports to          Director, Research
Location             Redwood City, CA
 
Responsibilities:
·      Independently generate and evaluate new methods, technologies and processes.
·      Design and execute experiments that ensure efficient and robust protocols
·      Achieve an ideal balance of assay integrity and work-flow simplicity through clever in-line quality control measures and assay monitoring strategies
·      Enable operational superiority through workflows compatible with automation
·      Assist in the design and execution of analytical and clinical validation studies
·     Act as a key contributor within integrated and multidisciplinary teams developing new and improving existing clinical assay.
·      Create and maintain SOPs in the context of CLIA/CAP environment
·      Perform calculations and data analysis
·      Generate new IP to maintain Karius’ leadership position in the field of infectious disease diagnostics.
·      Perform other duties, as needed
 
Travel:              No travel required
 
Physical Requirements: 
Subject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels. Work is generally performed in an office, lab or clinical environment.
 
Position Requirements:
·      PhD with minimum 5 years relevant experience building robust diagnostic products
·      Demonstrated proficiency taking clinical diagnostic assays through research and development
·      Experience with product development in CLIA/CAP or IVD environments
·      Follow GLPs and SOPs, and adhere to all safety and company policies
·      Expertise with RNA- and/or DNA-based Next-Generation Sequencing sample preparation technologies
 
Personal Qualifications:
·      Must be an excellent communicator and able to summarize key findings, risks in a succinct manner including the ability to present information to stakeholders
·      Ability to anticipate and identify potential roadblocks to meeting goals and identify corrective actions
·      Display a high level of commitment and professionalism and is truly passionate about being at the cutting edge of science and generating the appropriate clinical evidence
·      Ability to work independently, collaboratively and manage deadlines
·      Exemplary project management skills with the ability to build schedules and mitigate against timeline delays
·       Strong communication and presentation skills

At Karius, we value a diverse and inclusive workplace and provide equal employment opportunity for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company.  All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at recruiting@kariusdx.com and we will accommodate qualified individuals with disabilities.

 

Full-time
Redwood City, CA