Director of Core Data | Karius

Director of Core Data

About Karius
Karius is a venture-backed life science startup focused on transforming the way infectious diseases are diagnosed. Combining Next-Generation Sequencing and proprietary data analysis, we can identify over 1,000 pathogens from a single blood sample with typical turnaround time in one business day. By unlocking the information present in microbial cell-free DNA, we’re helping doctors quickly solve their most challenging cases, with a future vision of accelerating clinical trials, discovering new microbes, and reducing patient suffering worldwide.

Position Summary
You have mastered your craft yet you are still eager to learn and grow. You are highly curious and creative, efficient and effective. You already proved you have the ability to tackle complex problems. You want to make sure the time you pour into your next endeavor has the impact it deserves, and you will pursue that mission humbly.

Why Should You Join Us?
Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions. The Karius test we provide today is one of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients. Our test is the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission. You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale.

Reports to: CTO

Location: Redwood City, CA

Primary Responsibilities
•  Formulate the core biological data science strategies surrounding our core data assets, and drive roadmapping, execution, and delivery of data pipelines.
•  Design and implement systematic approaches to review, clean, analyze and integrate large and complex external datasets of value to our analytical pipeline and downstream interpretation of results.
•  Provide deep technical guidance on the mathematical, technological and the domain of biological data science.
•  As Karius' need for core data science expands, build up the core data science organization as a high-throughput, top-quality, collaborative group. 
•  Be the guardian of quality for our core data science practices and deliverables, participating in data quality review activities and efforts to resolve data quality issues.
•  Contribute to methods to ensure clinical data integrity and quality throughout the data lifecycle, ensuring appropriate blinding and study subject identity protection.
•  Work closely with the product, engineering, medical, and scientific teams, to set our company's goals, and partner in the development of our next products.
•  Provide an up-to-date view of current data opportunities and standards
•  Further innovate around accelerating value creation via R&D and streamlining operation.
•  Be a champion for effective mentorship and recruiting.

What's Fun About the Job?
Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters.

Travel:  No travel required.

Physical Requirements
Subject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels. Work is generally performed in an office environment.

Position Requirements
•  Ph.D. in CS, EE, or statistics.
•  First-author publications in top journals involving data quality and data platforms, preferably as it relates to biology and/or medicine.
•  Familiarity with key databases in our domain, including development of tools and architectures around these.
•  7+ years industry experience, including at a known company or large research institution.
•  4+ years management experience.
•  3+ experience implementing large-scale data platforms, building modern ETL and ELT solutions for data-warehouses, data lakes, and dash-mesh solutions.
•  2+ years designing, developing, deploying, and maintaining multi-service architectures.
•  2+ years of AWS, GCP, or Azure experience.

Personal Qualifications
•  Excellent written, verbal, and presentation skills.
•  Ability to thrive in a fast-paced startup environment and prioritize effectively.
•  Ability to work independently and be a self-motivator.
•  Detail oriented with excellent organizational and self-management skills.
•  Ability to perform multiple tasks, proactively plan, adhere to timelines, and have a creative approach to problem solving.
•  Has curiosity and is passionate about having an impact on patient’s lives.

At Karius, we value a diverse and inclusive workplace and provide equal employment opportunity for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company.  All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at and we will accommodate qualified individuals with disabilities. 

Redwood City, CA